BDBM50257963 2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine::CHEMBL494947

SMILES Clc1cccc(COc2cncc(n2)N2CCNCC2)c1

InChI Key InChIKey=PCWGGOVOEWHPMG-UHFFFAOYSA-N

Data  3 KI  1 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257963   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50257963(2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine |...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in tsA201 cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50257963(2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine |...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as accumulation of IP1 incubated for 1 hr at 37 degC followed by 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50257963(2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine |...)
Affinity DataEC50:  76nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed